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A special symposium celebrating the 50th anniversary of the Protein Data Bank

PDB50 will mark an important milestone in the history of structural biology. In 1971, the structural biology community established the single worldwide archive for macromolecular structure data — the (PDB). From its inception, the PDB has embraced a culture of open access, leading to its widespread use by the research community. PDB data are used by hundreds of data resources and millions of users exploring fundamental biology, energy and biomedicine.

Structural biology and structural bioinformatics have had an enormous impact on our understanding of the mechanism and function of biological macromolecules. The PDB acts as a custodian for all these data, representing a repository of the vast majority of the achievements and milestones of the structural biology community. The archive is managed by the (wwPDB) of partner sites in Asia, Europe and America.

This celebration of the 50th anniversary of the founding of the Protein Data Bank as the first open access digital data resource in biology will include presentations from speakers from around the world who have made tremendous advances in structural biology and bioinformatics. Students and postdoctoral fellows are especially encouraged to attend and will be eligible for poster prizes.

Organizers

• Celia Schiffer, University of Massachusetts Medical School
• Helen M. Berman, Rutgers, The State University of New Jersey; RCSB PDB
• Stephen K. Burley, Rutgers, The State University of New Jersey; RCSB PDB
• Jeffrey C. Hoch, University of Connecticut; BMRB
• Gerard J. Kleywegt, European Bioinformatics Institute; PDBe
• Genji Kurisu, Osaka University; PDBj
• John L. Markley, University of Wisconsin–Madison; BMRB
• Sameer Velankar, European Bioinformatics Institute; PDBe
• Christine Zardecki, Rutgers, The State University of New Jersey; RCSB PDB

Acknowledgement:  by David S. Goodsell, The Scripps Research Institute. doi: 10.2210/rcsb_pdb/goodsell-gallery-003

This illustration shows a cross-section through the blood, with blood serum in the upper half and a red blood cell in the lower half. In the serum, look for Y-shaped , long thin molecules (in light red) and many small proteins. The large UFO-shaped objects are low density lipoprotein and the six-armed protein is complement C1. The red blood cell is filled with , in red. The cell membrane, in purple, is braced on the inner surface by long spectrin chains connected at one end to a small segment of actin filament.