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Member spotlight: Mohammad Masood

is a Ph.D. student at Jamia Millia Islamia, New Delhi, India.

What is your research focus?

“My research focuses on studying endothelial nitric oxide synthase (eNOS) acetylation and phosphorylation, and their effects on uncoupled nitric oxide synthesis, tetrahydrobiopterin (BH4) recycling and superoxide generation.”

What is the broader impact of your work?

“The broader impact of my research lies in advancing our understanding of endothelial nitric oxide synthase (eNOS) regulation, which has critical implications for cardiovascular health. By elucidating the mechanisms of eNOS acetylation, phosphorylation and uncoupling, this work could contribute to developing therapeutic strategies for conditions such as hypertension, atherosclerosis and other vascular diseases where nitric oxide imbalance and oxidative stress play a key role. It may lead to better treatments targeting endothelial dysfunction, ultimately improving patient outcomes in a range of chronic diseases.”

What are you watching/reading outside the lab/work?

“Outside the lab, I enjoy reading a mix of science and non-science content to maintain a balance. On the science front, I'm currently exploring "The Machinery of Life" by David Goodsell, which beautifully visualizes molecular processes. For a break from research, I'm reading "Sapiens: A Brief History of Humankind" by Yuval Noah Harari, which offers fascinating insights into the history of human civilization. Both help me stay curious and inspired in and out of the lab.”

What music or podcasts have you been enjoying lately?

“Lately, I’ve been enjoying the podcast "Song Exploder." It dives into the creative process behind popular songs, where artists break down how they composed and produced their tracks. I find it inspiring because, much like research, it shows how complex ideas can come together from small, seemingly simple elements. It's a great way to unwind while still appreciating creativity.”

Who are your heroes/heroines?

“My heroes and heroines are those who have made significant contributions to science and humanity, particularly those whose work transcends the lab and has a real-world impact. People like Marie Curie, whose pioneering research in radioactivity paved the way for modern medical treatments, and Sir Paul Nurse, for his work in cell cycle regulation, are major inspirations for me. Outside of science, I admire individuals like Malala Yousafzai, for her courage and advocacy for education, and Elon Musk, for his visionary approach to technology and sustainability. These figures inspire me to think boldly and act with purpose in my research and beyond.”

What have you learned from your work that applies to the rest of your life?

“One key lesson I've learned from my work is the value of persistence and adaptability. Research, especially in molecular enzymology, often involves setbacks and experiments that go differently than planned. This has taught me that progress, whether in science or life, requires patience, resilience and the willingness to adapt when things don't work out. Additionally, the importance of data-driven decision making in research has influenced my approach to solving my problems outside the lab. It reminds me to base my choices on facts rather than assumptions.”

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