Greener neighborhoods can protect us — at the molecular level
A new study finds that greenspace – the vegetation in a neighborhood’s yards, parks and public spaces – has a positive impact on a key genetic marker associated with exposure to stress. However, the study also finds that the positive impact of greenspace isn’t enough to compensate for other environmental challenges, such as air pollution.
The markers in question are telomeres, which are sections of repetitive DNA found at each end of a chromosome that serve to protect the ends of the chromosomes from damage. However, each time a cell divides, the telomeres inside those cells become slightly shorter. Once the telomeres become so short that the cell cannot divide successfully, the cell dies.
“This makes telomeres important markers of biological age, or how worn down our cells are,” says Scott Ogletree, corresponding author of a paper on the study and a former postdoctoral researcher at North Carolina State University’s Center for Geospatial Analytics. “And we know that many variables – such as stress – can influence how quickly our telomeres wear down.” Ogletree is now a lecturer at the University of Edinburgh.
“There’s a lot of research that talks about the various ways in which greenspace is beneficial, and a lot of research that talks about adverse health effects associated with pollution, racist segregation in housing, and other social and environmental challenges,” says Aaron Hipp, co-author of the study and a professor of parks, recreation and tourism management at NC State. “This study was an attempt to quantify the beneficial impacts of greenspace at the cellular level, and the extent to which greenspace can help to offset environmental harms.”
For the study, researchers drew on data from the CDC’s National Health and Nutrition Examination Survey (NHANES) for the years 1999-2002. NHANES is a longitudinal, nationally representative study that assesses the health of the U.S. population through interviews and physical examinations.
Specifically, the researchers looked at data on 7,827 people that allowed them to assess their demographic data, the length of their telomeres, and where they lived. The research team assessed the amount of greenspace in each person’s neighborhood and how that related to their telomere length. The researchers also accounted for potential confounding variables, such as lifestyle, health history and substance use. In addition, the researchers identified a suite of other environmental variables that could affect telomere length, such as air quality and “redlining” maps that track historically segregated neighborhoods.
“We found that the more greenspace people had in their neighborhoods, the longer their telomeres were,” says Hipp, who is also the associate director of social and behavioral science applications at NC State’s Center for Geospatial Analytics. “That was true regardless of race, economic status, whether they were drinkers or smokers, etc.”
“That’s the good news,” Ogletree says. “However, when we accounted for other characteristics of each neighborhood – air pollution, segregation, or ‘deprivation’ – the positive effect of the greenspace essentially disappeared. Deprivation, in this context, was an overarching variable that included the neighborhood-level data on income, education, employment status, and housing conditions. In other words, while greenspace seems to help protect telomere length, the harm from other factors appears to offset that protection.”
“Greenspace is tremendously valuable for a community, but it is not enough to overcome systemic racism and the effects of economic segregation and environmental justice challenges on its own,” says Hipp. “This study drives home the idea that creating greenspace in a community is important, but it’s as crucial – or more crucial – for us to address environmental harms, particularly those tied to systemic racism.”
This article was first published by North Carolina State University.
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition weekly.
Learn moreGet the latest from ASBMB Today
Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles
Transforming learning through innovation and collaboration
Neena Grover will receive the William C. Rose Award for Exemplary Contributions to Education at the 2025 ASBMB Annual Meeting, April 12–15 in Chicago.
Guiding grocery carts to shape healthy habits
Robert “Nate” Helsley will receive the Walter A. Shaw Young Investigator in Lipid Research Award at the 2025 ASBMB Annual Meeting, April 12–15 in Chicago.
Quantifying how proteins in microbe and host interact
“To develop better vaccines, we need new methods and a better understanding of the antibody responses that develop in immune individuals,” author Johan Malmström said.
Leading the charge for gender equity
Nicole Woitowich will receive the ASBMB Emerging Leadership Award at the 2025 ASBMB Annual meeting, April 12–15 in Chicago.
CRISPR gene editing: Moving closer to home
With the first medical therapy approved, there’s a lot going on in the genome editing field, including the discovery of CRISPR-like DNA-snippers called Fanzors in an odd menagerie of eukaryotic critters.
Finding a missing piece for neurodegenerative disease research
Ursula Jakob and a team at the University of Michigan have found that the molecule polyphosphate could be what scientists call the “mystery density” inside fibrils associated with Alzheimer’s, Parkinson’s and related conditions.